Laurell K. Hamilton has a serious winner in her Anita Blake: Vampire Hunter series. She manages to be funny, erotic, witty, and downright weird and tie it all up in a really cool package. Vampires, Werewolves and Executioners, oh my!
Fred Saberhagen Has a really great Vampire series staring Vald Dracula himself! The first tells Bram Stoker's classic from the Count's own view point...